Table 3.
Effect of rosuvastatin (Ros) and atorvastatin (Ator) on the biochemical parameters of rats at week 10
Animal group |
Sham (II)
(n=8) |
HCD (III)
(n=8) |
HCD + ROS (IV)
(n=8) |
HCD + ATOR (V)
(n=8) |
||||
---|---|---|---|---|---|---|---|---|
Before | After | Before | After | Before | After | Before | After | |
Urea (mg/dl) | 50.37 ± 7.00 | 53.00 ± 6.76 | 44.00 ± 8.71 | 47.75 ± 6.54 | 45.87 ± 7.88 | 50.87 ± 6.55 | 45.50 ± 10.65 | 52.37 ± 6.58 |
Creatinine (mg/dl) | 0.44 ± 0.10 | 0.41 ± 0.03 | 0.47 ± 0.13 | 0.45 ± 0.10 | 0.46 ± 0.04 | 0.34 ± 0.07 | 0.47 ± 0.22 | 0.37 ± 0.06 |
Calcium (mg/dl) | 8.17 ± 0.92 | 8.56 ± 0.96 | 8.9 ± 0.74 | 8.97 ± 0.89 | 9.17 ± .94 | 8.18 ± 0.61 | 8.59 ± 0.45 | 8.40 ± 0.71 |
Phosphorus (mg/dl) | 5.07 ± 0.85 | 5.45 ± 1.08 | 5.45 ± 0.96 | 5.32 ± 1.00 | 5.38 ± 0.58 | 5.33 ± 0.07 | 5.40 ± 0.74 | 5.32 ± 1.01 |
Sham, rats fed with normal diet+water gavage; HCD, rats fed with hypercholesterolemic diet; HCD+Ros, rats fed with hypercholesterolemic diet+Ros (20 mg/kg); HCD+Ator, rats fed with hypercholesterolemic diet+Ator (20 mg/kg). Values are expressed as the means±SD. No differences between groups before and after treatment