Table 5.

Effect of rosuvastatin (Ros) and atorvastatin (Ator) on tubulointerstitial damage in kidney tissues of rats

HCD + ATRO (V) (n=8)	HCD + ROS(IV) (n=8)	HCD (III) (n=8)	Sham (II) (n=8)	Control ) I ( (n=8)	Variable
1.08 ± 0.09b,c	1.46 ± 0.19b	2.00 ± 0.13 a	0.15 ±0.07	0.12 ± 0.08	TID

Control, rats fed with normal diet; Sham, rats fed with normal diet+water Gavage; HCD, rats fed with hypercholesterolemic diet; HCD+ROS, rats fed with hypercholesterolemic diet+Ros (20 mg/kg); HCD+Ator, rats fed with hypercholesterolemic diet+Ator (20 mg/kg); TID, tubulointerstitial damage. Values are expressed as the means±SD

Semi quantitative analysis of TID scores in the study groups. The TID score in HCD group was significantly (P=0.001) higher than the control and sham groups. The TID scores in (Ator+HCD) and (Ros+HCD) were semi quantitative lower than HCD group

^a P<0.01vs. Sham and control group; ^b P<0.01 vs. HCD; ^c P<0.01vs. HCD+Ros