Table 4.
Multivariate analysis of factors influencing survival according to age using a Cox proportional hazards model
| Characteristic |
≤ 60 yr old |
> 60 yr old |
||||
| P value | HR | 95%CI | P value | HR | 95%CI | |
| Sex | ||||||
| Male | 1.000 | 1.000 | ||||
| Female | 0.300 | 1.116 | 0.907-1.373 | 0.017 | 0.780 | 0.636-0.957 |
| Tumour size | ||||||
| ≤ 5 cm | 1.000 | 1.000 | ||||
| > 5 cm | 0.001 | 1.973 | 1.586-2.454 | 0.086 | 1.187 | 0.976-1.444 |
| Lymphovascular invasion | ||||||
| No | 1.000 | 1.000 | ||||
| Yes | 0.001 | 1.783 | 1.441-2.206 | 0.001 | 1.580 | 1.307-1.910 |
| Lymph node metastasis | ||||||
| No | 1.000 | 1.000 | ||||
| Yes | 0.485 | 0.929 | 0.756-1.142 | 0.147 | 0.872 | 0.725-1.049 |
| Depth of invasion | ||||||
| Muscularis propria | 0.185 | 0.570 | 0.249-1.308 | 0.371 | 0.746 | 0.392-1.418 |
| Sub-serosal | 0.280 | 0.638 | 0.283-1.441 | 0.472 | 0.792 | 0.420-1.495 |
| Serosal exposed | 0.214 | 0.594 | 0.262-1.350 | 0.465 | 0.786 | 0.412-1.500 |
| Serosal invasion | 0.518 | 0.724 | 0.272-1.929 | 0.549 | 0.765 | 0.318-1.839 |
| Histology | ||||||
| Tubular adenocarcinoma (well) | 1.000 | 1.000 | ||||
| Tubular adenocarcinoma (moderate) | 0.731 | 0.891 | 0.463-1.718 | 0.010 | 2.547 | 1.246-5.205 |
| Tubular adenocarcinoma (poorly) | 0.929 | 0.972 | 0.514-1.837 | 0.004 | 2.812 | 1.380-5.730 |
| Signet ring cell carcinoma | 0.427 | 1.309 | 0.674-2.543 | 0.001 | 3.652 | 1.700-7.843 |
| Mucinous adenocarcinoma | 0.134 | 0.525 | 0.226-1.220 | 0.002 | 3.847 | 1.648-8.979 |
HR: Hazard ratio; CI: Confidence interval.