Table 5.
Analysis of lymph node metastasis using the chi-squared test and a logistic regression model
| Characteristic |
Lymph node metastasis |
Univariate |
Multivariate |
|||
| Yes | No | P value | OR | 95%CI | P value | |
| Sex | ||||||
| Male | 766 (71) | 618 (66.7) | 0.040 | 1.000 | ||
| Female | 313 (29) | 308 (33.3) | 0.840 | 0.682-1.034 | 0.099 | |
| Age | ||||||
| ≤ 60 yr | 573 (53.1) | 496 (53.6) | 0.837 | 1.000 | ||
| > 60 yr | 506 (46.9) | 430 (46.4) | 1.035 | 0.854-1.255 | 0.726 | |
| Tumour size | ||||||
| ≤ 5 cm | 580 (53.8) | 316 (34.1) | 0.001 | 1.000 | ||
| > 5 cm | 499 (46.2) | 610 (65.9) | 0.552 | 0.453-0.674 | 0.001 | |
| Lymphovascular invasion | ||||||
| Yes | 415 (38.5) | 608 (65.7) | 0.001 | 0.356 | 0.294-0.431 | 0.001 |
| No | 664 (61.5) | 318 (34.3) | 1.000 | |||
| Depth of invasion | ||||||
| Muscularis propria | 252 (23.4) | 252 (27.2) | 0.647 | 0.297-1.409 | 0.273 | |
| Sub-serosal | 453 (42) | 412 (44.5) | 0.711 | 0.329-1.537 | 0.386 | |
| Serosal exposed | 327 (30.3) | 233 (25.2) | 0.908 | 0.418-1.975 | 0.808 | |
| Serosal invasion | 30 (2.8) | 18 (1.9) | 1.078 | 0.414-2.809 | 0.877 | |
| Histology | ||||||
| Tubular adenocarcinoma (well) | 46 (4.3) | 16 (1.8) | 0.011 | 1.000 | ||
| Tubular adenocarcinoma (moderate) | 342 (32.3) | 282 (31) | 0.560 | 0.301-1.043 | 0.068 | |
| Tubular adenocarcinoma (poorly) | 519 (49) | 473 (52) | 0.583 | 0.315-1.080 | 0.086 | |
| Signet ring cell carcinoma | 119 (11.2) | 100 (11) | 0.676 | 0.347-1.318 | 0.251 | |
| Mucinous adenocarcinoma | 33 (3.1) | 38 (4.2) | 0.474 | 0.218-1.029 | 0.059 | |
OR: Odds ratio; CI: Confidence interval.