Table 1.
Comparison of Variables Between Mastectomy + Radiotherapy (MXRT) and Radiotherapy Only (XRT) Groups in the Original Dataset and Matched Dataset
| Original Dataset | Matched Dataset | |||||||
|---|---|---|---|---|---|---|---|---|
| Variables | MXRT | XRT | SMD* | p-value | MXRT | XRT | SMD* | p-value |
| Number of Patients | 244 (56.2) | 190 (43.8) | - | - | 173 (50.0) | 173 (50.0) | - | - |
| Age | 0.266 | 0.010 | 0.041 | 0.974 | ||||
| <50 | 67 (27.4) | 27 (14.2) | 29 (16.8) | 26 (15.0) | ||||
| 50-59 | 78 (32.0) | 68 (35.8) | 64 (37.0) | 64 (37.0) | ||||
| 60-69 | 60 (24.6) | 57 (30.0) | 47 (27.2) | 49 (28.3) | ||||
| >69 | 39 (16.0) | 38 (20.0) | 33 (19.1) | 34 (19.7) | ||||
| Race | 0.057 | 0.445 | 0.059 | 0.858 | ||||
| White | 195 (79.9) | 153 (80.5) | 137 (79.2) | 141 (81.5) | ||||
| Black | 37 (15.2) | 32 (16.8) | 30 (17.3) | 27 (15.6) | ||||
| Other | 12 (4.9) | 5 (2.6) | 6 (3.5) | 5 (2.9) | ||||
| Charlson-Deyo Score | 0.083 | 0.627 | 0.038 | 0.808 | ||||
| 0 | 201 (82.4) | 163 (85.8) | 147 (85.0) | 146 (84.4) | ||||
| 1 | 34 (13.9) | 21 (11.1) | 22 (12.7) | 21 (12.1) | ||||
| ≥2 | 9 (3.7) | 6 (3.2) | 4 (2.3) | 6 (3.5) | ||||
| Facility Type | 0.035 | 0.007 | 0.091 | 0.645 | ||||
| Non-Academic | 165 (67.6) | 122 (64.2) | 121 (69.9) | 113 (65.3) | ||||
| Academic | 62 (25.4) | 65 (34.2) | 49 (28.3) | 57 (32.9) | ||||
| Unknown | 17 (7.0) | 3 (1.6) | 3 (1.7) | 3 (1.7) | ||||
| Year of Diagnosis | 0.045 | 0.642 | 0.049 | 0.646 | ||||
| <2010 | 72 (29.5) | 60 (31.6) | 58 (33.5) | 54 (31.2) | ||||
| ≥2010 | 172 (70.5) | 130 (68.4) | 115 (66.5) | 119 (68.8) | ||||
| Pathologic N Stage | 0.030 | 0.917 | 0.021 | 0.711 | ||||
| 1 | 116 (47.5) | 94 (49.5) | 76 (43.9) | 81 (46.8) | ||||
| 2 | 69 (28.3) | 51 (26.8) | 55 (31.8) | 48 (27.7) | ||||
| 3 | 59 (24.2) | 45 (23.7) | 42 (24.3) | 44 (25.4) | ||||
| Clinical M Stage | 0.094 | 0.337 | <0.001 | 1.0 | ||||
| cM0 | 235 (96.3) | 186 (97.9) | 169 (97.7) | 169 (97.7) | ||||
| cMx | 9 (3.7) | 4 (2.1) | 4 (2.3) | 4 (2.3) | ||||
| ER† Status | 0.007 | 0.154 | 0.055 | 0.578 | ||||
| Negative | 71 (29.1) | 49 (25.8) | 53 (30.6) | 46 (26.6) | ||||
| Positive | 155 (63.5) | 134 (70.5) | 111 (64.2) | 120 (69.4) | ||||
| Unknown | 18 (7.4) | 7 (3.7) | 9 (5.2) | 7 (4.0)) | ||||
| PR‡ Status | 0.100 | 0.033 | <0.001 | 0.690 | ||||
| Negative | 125 (51.2) | 80 (42.1) | 80 (46.2) | 77 (44.5) | ||||
| Positive | 100 (41.0) | 101 (53.2) | 82 (47.4) | 88 (50.9) | ||||
| Unknown | 19 (7.8) | 9 (4.7) | 11 (6.4) | 8 (4.6) | ||||
| HER2/neu Status | 0.061 | 0.476 | 0.068 | 0.811 | ||||
| Negative | 116 (47.5) | 99 (52.1) | 84 (48.6) | 90 (52.0) | ||||
| Positive | 34 (13.9) | 20 (10.5) | 19 (11.0) | 18 (10.4) | ||||
| Unknown | 94 (38.5) | 71 (37.4) | 70 (40.4) | 65 (37.6) | ||||
| Hormonal Therapy | 0.055 | 0.821 | 0.042 | 0.904 | ||||
| No | 91 (37.3) | 67 (35.2) | 67 (38.7) | 63 (36.4) | ||||
| Yes | 145 (59.4) | 115 (60.5) | 99 (57.2) | 103 (59.5) | ||||
| Unknown | 8 (3.3) | 8 (4.2) | 7 (4.0) | 7 (4.0) | ||||
| Chemotherapy | 0.230 | 0.049 | 0.069 | 0.519 | ||||
| No | 22 (9.0) | 31 (16.3) | 20 (11.6) | 24 (13.9) | ||||
| Yes | 221 (90.6) | 159 (83.7) | 153 (88.4) | 149 (86.1) | ||||
| Unknown | 1 (0.4) | 0 (0) | - | - | ||||
| ALND§ | 0.068 | 0.676 | 0.055 | 0.852 | ||||
| No | 83 (34.0) | 72 (37.9) | 59 (34.1) | 64 (37.0) | ||||
| Yes | 154 (63.1) | 112 (58.9) | 109 (63.0) | 104 (60.1) | ||||
| Unknown | 7 (2.9) | 6 (3.2) | 5 (2.9) | 5 (2.9) | ||||
*
Standardized mean difference
†
Estrogen receptor
‡
Progesterone receptor
§
Axillary lymph node dissection