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Response rates reported in primary analysis (BOLT study) [23]
| 200 mg sonidegib laBCC: 42 | 800 mg sonidegib laBCC: 93 | 200 mg sonidegib mBCC: 13 | 800 mg sonidegib mBCC: 23 | |
|---|---|---|---|---|
| ORR% (95% CI) | 43% (28–59) | 38% (28–48) | 15% (2–45) | 17% (5–39) |
| CR% | 5% | 0 | 0 | 0 |
| Duration of response (median, months) | Not reached | Not reached | Not reached | 8.3 (not estimable) |
| Progression-free survival (median, months) | Not reached | Not reached | 13.1 | 7.6 |
| Time to tumor response (median, months) | 3.9 | 3.7 | 4.6 | 1 |
