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. Author manuscript; available in PMC: 2020 Oct 27.
Published in final edited form as: Nat Cell Biol. 2020 Apr 27;22(5):570–578. doi: 10.1038/s41556-020-0501-4

Extended Data Fig. 3. Lis1 does not increase the stall duration of dynein bound to dynactin and a cargo adaptor.

Extended Data Fig. 3

(a) Inverse cumulative distribution of stall durations in the absence and presence of 600 nM Lis1. Solid curves represent fitting to a two-exponential decay (decay time ± SE). (b) Mean stall times of mtDDB and mtDDR in absence and presence of 600 nM Lis1 (± SEM). p values are calculated from a two-tailed t-test. In a and b, n = 53, 27, 50, and 39 from left to right, four independent experiments per condition.