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. Author manuscript; available in PMC: 2020 May 11.
Published in final edited form as: JAMA Netw Open. 2020 Feb 5;3(2):e1921043. doi: 10.1001/jamanetworkopen.2019.21043

Table 3. The Association between Depression and All-cause and Cardiovascular Mortality: Stratified Analysis by Sex.

Case/person-years Incidence per 1,000 person-years HR (95% CI)a P for interactionb
All-cause mortality
      CKB
              Male 25,151/2,049,266 12.27 1.53 (1.32-1.76) .005
              Female 18,914/3,039,543 6.22 1.19 (1.03-1.37)
      DFTJ
              Male 1659/91,681 18.10 1.24 (1.10-1.41) .21
              Female 912/116,723 7.81 1.06 (0.91-1.24)
CVD mortality
      CKB
              Male 9796/2,049,266 4.78 1.39 (1.10-1.76) .10
              Female 7852/3,039,543 2.58 1.11 (0.89-1.40)
      DFTJ
              Male 656/91,681 7.16 1.49 (1.23-1.80) .06
              Female 357/116,723 3.06 1.09 (0.86-1.39)

Abbreviation: CI, confidence interval; CKB, China Kadoorie Biobank; CVD, cardiovascular diseases; DFTJ, Dongfeng-Tongji; HR, hazard ratio.

a

The model adjusted age, sex, education, BMI, spouse, drinking, smoking, consumption of meat, vegetables, fruits, health index and family history of CVD; CKB cohort further adjusted region and household income.

b

The results were calculated by adjusting for confounders shown above.