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. Author manuscript; available in PMC: 2020 May 11.
Published in final edited form as: JAMA Netw Open. 2020 Feb 5;3(2):e1921043. doi: 10.1001/jamanetworkopen.2019.21043

Table 4. The Association between Depression and All-cause and Cardiovascular Mortality: Stratified Analysis by Age.

Case/person-years Incidence per 1,000 person-years HR (95% CI)a P for interactionb
All-cause mortality
    CKB
        Age≥65 21,230/67,1594 31.81 1.08 (0.91-1.29) <.001
        Age <65 22,835/4,417,216 5.17 1.45 (1.28-1.64)
    DFTJ
        Age ≥65 1858/84,654 21.95 1.21 (1.08-1.35) .39
        Age <65 713/123,750 5.76 1.06 (0.88-1.28)
CVD mortality
    CKB
        Age ≥65 9838/671,594 14.65 1.01 (0.78-1.32) .02
        Age <65 7810/4,417,216 1.76 1.34 (1.09-1.65)
    DFTJ
        Age ≥65 761/84,654 8.99 1.33 (1.12-1.58) .98
        Age <65 252/123,750 2.04 1.27 (0.94-1.71)

Abbreviation: CI, confidence interval; CKB, China Kadoorie Biobank; CVD, cardiovascular diseases; DFTJ, Dongfeng-Tongji; HR, hazard ratio.

a

The model adjusted age, sex, education, BMI, spouse, drinking, smoking, consumption of meat, vegetables, fruits, health index and family history of CVD; CKB cohort further adjusted region and household income.

b

The results were calculated by adjusting for confounders shown above.