Table 1. Baseline characteristics between patients with and without manometry performed at IPC insertion.
| Baseline characteristics | Patients who had manometry at IPC insertion (N=113) | Patients without manometry at IPC insertion (N=125) | Statistical difference |
|---|---|---|---|
| Age (median, IQR) | 70.0 [60–77] | 67.0 [57–75] | P=0.12 |
| Male:female | 54:59 (48%:52%) | 62:63 (50%:50%) | P=0.78 |
| Smoking status | Never smoked 47 (42%), ex-smoker 57 (50%), current smoker 9 (8%) | Never smoked 39 (31%), ex-smoker 69 (55%), current smoker 17 (14%) | P=0.15 |
| WHO performance status | 0 =9 (8%), 1 =57 (50%), 2 =34 (30%), 3 =13 (12%), 4 =0 (0%) | 0 =8 (6%), 1 =53 (42%), 2 =38 (30%), 3 =23 (18%), 4 =3 (2%) | P=0.068 |
| IPC insertion side | Left 41 (36%), right 72 (64%) | Left 53 (42%), right 72 (58%) | P=0.34 |
| Pleural interventions in last 3 months | No =27 patients (24%), yes =86 patients (76%) (139 procedures) (median =1, IQR 1.0–2.0) | No =38 (30%), yes =87 (70%) (140 procedures) (median =1, IQR 1.0–2.0) | P=0.26 for any intervention |
| Underlying malignancy | Lung =38, breast =22, mesothelioma =14, unspecified =10, ovarian =7, gastrointestinal tract =7, other =13 | Lung =41, breast =26, mesothelioma =14, ovarian =9, gastrointestinal tract =8, unspecified =3, other =23 | |
| Fluid drained at IPC insertion (litres) (median & IQR) | All manometry =1.11 (0.90–1.34), no-UL =1.05 (1.00–1.31), P-UL =1.00 (0.75–1.40), S-UL =1.25 (0.98–1.32) | All non-manometry: 1.00 (0.75–1.30) | P=0.018 for manometry vs. non-manometry. P=0.90 for UL groups in manometry subset |
| Fluid drained between insertion and day 10 (excluding initial drainage) (litres) (median & IQR) | All manometry =3.3 (2.02–4.30), no-UL =3.48 (1.98–4.23), P-UL =3.14 (2.55–3.95), S-UL =2.05 (1.85–4.46) | All non-manometry: 2.80 (2.05–3.80) | P=0.12 for manometry vs. non-manometry. P=0.90 for UL groups in manometry subset |
| Fluid removed at closing pleural pressure measurement (litres) (median & IQR) | No-UL =0.96 (0.80–1.20), P-UL =1.00 (0.80–1.30), S-UL =0.90 (0.76–1.10), No+P-UL =0.98 (0.80–1.20) | N/A | P=0.94 between 3 radiographic groups. P=0.60 between 2 radiographic groups |
IQR, interquartile range.