A

Exposure factor	Genotype	TBP	CC	NCC	TC
Occupational biomass smoke		n = 45	n = 76	n = 42	n = 118
	GG, n (%)	44 (97.8)	69 (90.8)	34 (81)	103 (87.3)
	GA, n (%)	1 (2.2)	6 (7.9)	8 (19)	14 (11.9)§
	AA, n (%)	0	1 (1.3)	0	1 (0.8)
In-home biomass smoke		n = 55	n = 79	n = 39	n = 118
	GG, n (%)	54 (98.2)	72 (91.1)	32 (82.1)	104 (88.1)
	GA, n (%)	1 (1.8)	6 (7.6)	7 (17.9)	13 (11)¥
	AA, n (%)	0	1 (1.3)	0	1 (0.9)
Cigarette intake		n = 98	n = 106	n = 60	n = 166
	GG, n (%)	94 (95.9)	98 (92.5)	51 (85)	149 (89.8)
	GA, n (%)	4 (4.1)	7 (6.6)	9 (15)*	16 (9.6)
	AA, n (%)	0	1 (0.9)	0	1 (0.6)
Alcohol intake		n = 95	n = 99	n = 57	n = 156
	GG, n (%)	92 (96.8)	90 (90.9)	47 (82.5)	137 (87.8)
	GA, n (%)	3 (3.2)	8 (8.1)	10 (17.5)	18 (11.6)†
	AA, n (%)	0	1 (1)	0	1 (0.6)

^§p = 0.04, OR = 0.16, 95% CI: 0.01–0.92;

^¥p = 0.02, OR = 0.14, 95% CI: 0.01–0.81;

^*p = 0.02, OR = 0.24, 95% CI: 0.06–0.92;

^†p = 0.01, OR = 0.24, 95% CI: 0.05–0.75. PTB – tuberculosis patients, CC – consanguineous controls, NCC – nonconsanguineous controls, TC – total controls.