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HO-1 suppressed the TGF-β signaling pathway in NASH-related liver fibrosis mice. (a) Hepatic mRNA and (b) protein levels of fibrosis-related genes TGF-β1, α-SMA, Col-1, Smad4, p-Smad2, and p-Smad3. β-Actin was used as the loading control. Values are mean ± SD; ∗∗P < 0.01 vs. the control group; #P < 0.05, ##P < 0.01 vs. the MCD group.
