Figure 2.

Zinc preconditioning reduced the increase in serum AST and ALT levels after liver IRI. Serum ALT (A) and AST (B) concentrations (mean ± SEM [units/L]) in rats treated with saline (control) (●) and 10 mg/kg of ZnCl₂ (▪). The rise in serum ALT and AST levels was less in rats preconditioned with 10 mg/kg of ZnCl₂ than in the saline control group. (C) Mean percentage weight change from baseline weight between zinc treatment and control groups. ZnCl₂ preconditioning improves the health of rats after IRI. Weight loss was observed in both the groups after liver IRI; however, the rats preconditioned with 10 mg/kg of ZnCl₂ appeared to have an earlier return to weight gain than the saline control group rats, although these changes were not statistically significant. *p < 0.05 vs saline-treated control. AST, aspartate transaminase; ALT, alanine transaminase; SEM, standard error of mean; IRI, ischaemia-reperfusion injury.