Table 1.
Group | Neutrophilic infiltration score (0–4) | Average score | Criteria for assessing neutrophil infiltration |
---|---|---|---|
Saline control (n = 5) | 2 | 1.8 | Neutrophil infiltration expressed as neutrophil count per 50 high-power fields 0 = <15 (none/scant) 1 = 16 to 50 (minimal) 2 = 51 to 100 (mild) 3 = 101 to 250 (moderate) 4 = >250 (severe) |
2 | |||
1 | |||
2 | |||
2 | |||
Zinc (10 mg/kg) (n = 5) |
1 | 0.6 (p = 0.016) |
|
1 | |||
0 | |||
0 | |||
1 |
Group | Liver necrosis score (0–4) | Average score | Criteria for assessing liver necrosis |
---|---|---|---|
Saline control (n = 5) | 3 | 2 | Liver necrosis assessed as the degree of hepatocellular necrosis 0 = None 1 = Single-cell apoptosis 2 = Lobular confluent necrosis <30% 3 = Lobular confluent necrosis 31–60% 4 = Lobular confluent necrosis >60% |
2 | |||
1 | |||
2 | |||
2 | |||
Zinc (10 mg/kg) (n = 5) | 1 | 0.8 (p = 0.012) | |
1 | |||
1 | |||
1 | |||
0 |
A grading scale of 0–4, as outlined by Suzuki et al,18 was used for the histopathological analysis of neutrophil infiltration and necrosis in the liver.