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. 2020 Jan 22;2020:9705358. doi: 10.1155/2020/9705358

Table 1.

Considered diagnostic tests for Schistosomiasis haematobium in the Moroccan survey.

Diagnostic Test Field Cost/test (USD) Evaluation Sensitivity/specificity Note Ref
Clinical test Hem test1 + 0, 3 Iraq, Ghana, Sudan, Tanzania, Nigeria, Sub Saharan Africa 79%/98% Morbidity test [26]

Antibodies detection HAMA EITB2 _ >5 Morocco USA 95%/100% High cost and not field-friendly [12, 23]
EITB/WB 23kDa3 _ 8, 8 Egypt and Morocco 50/91% High cost and not field-friendly [23, 24]
ELISA-SEA4 (soluble eggs antigen) + 8, 8 Ghana 98.5%/83%/93% High cost [23, 25]
Need laboratory
HAI5(whole adult worm antigen) + 2.5 Germany, Chile and Netherlands 92%/94.7% Acceptable [2526]
DDIA6 + 1 China -- Need evaluation in haematobium low endemic areas [28]
RDT SmCTF7 + <3 Ivory Coast 66.7%/34.4% Not acceptable [29]

Antigen detection Filtration _ <3 Africa, Iran, Iraq Need laboratory [30]
RDT filtration + <3 USA, Kenya 79%/95% Field friendly and cost effectiveness, but not hygienic in large number of samples [31]
POC CCA8 + 3 Cameroun, Ivory Coast Ethiopia, Kenya, Uganda 36%/78% Not sensitive in haematobium low endemic areas [32, 33]
Zanzibar 99% [30]
PCR9 _ 8 Brazil 100% High cost [20, 33]

1. Urine hemedipstick, 2. Heamatobium microsomal antigen enzyme Immunotransfert Blot, 3. 23 kDa Western blot, 4. Soluble eggs antigen enzyme linked

immunosorbent assay, 5. Hemmaglutination indirect, 6. Dipstick dye immunoassay, 7. Schistosoma mansoni cercarial transformation fluid, 8. Point of care/circulating cathodic Antigen, 9. Polymerase chain reaction.