Table 1.

Patient characteristics and differences between patients with good and poor neurological outcome.

	Good outcome N = 32	Poor outcome N = 106	p-value
Female sex	14/32 (44%)	20/106 (19%)	<0.01
Mean age (±SD)	65.9 ± 11	66.7 ± 11.2	0.9
OHCA	30/32 (94%)	92/106 (87%)	0.4
Cardiac etiology	28/29 (97%)	74/93 (80%)	0.2
Shockable rhythm (VF or VT)	31/32 (97%)	67/106 (63%)	<0.01
Mild therapeutic hypothermia (33°C)*	27/32 (84%)	54/105 (51%)	<0.01
Propofol in first 24 h	30/31 (97%)	84/102 (82%)	0.05
Max propofol dose in first 24 h (mg/kg/h)	2.62 ± 1.10	2.59 ± 1.06	0.9
Midazolam in first 24 h	8/31 (26%)	37/102 (36%)	0.4
Max midazolam dose in first 24 h (μg/kg/h)	166.9 ± 82.4	165 ± 90.2	0.7
Suppressed, or synchronous patterns on suppressed background at 12 h	0/25 (0%)	39/72 (54%)	<0.01
Suppressed, or synchronous patterns on suppressed background at 24 h	0/30 (0%)	32/93 (34%)	<0.01
Bilaterally absent SSEP**	0/31 (0%)	41/98 (42%)	<0.01
Continuous EEG at 12 h	6/25 (24%)	2/64 (3%)	<0.01

SD, standard deviation; OHCA, out of hospital cardiac arrest; VF, ventricular fibrillation; unfavorable, suppressed, low-voltage, or synchronous patterns with suppressed background; SSEP, somatosensory evoked potential; unknown variables were treated as missing variables.

^*The remainder of patients was treated at 36°C.

^**Bilaterally absent SSEP generally between 48–72 h, never within 24 h after cardiac arrest and only 1 measurement per patient.