TABLE 1.
Putative functions and orthologous genes for horizontally acquired genes.
| Order in the HGT region | S. cerevisiae strain | EC1118 or S288C | |
| (annotation name)* | (donor species) | Hypothetical function | ortholog |
| A1 (0012) | ALL (Torulaspora sp.) | Hypothetical protein, putative monoxygenase | No ortholog found |
| A2 (0023) | ALL (Torulaspora sp.) | Enoyl reductase-like, probably dehydrogenase (D-arabinose 1-dehydrogenase) | YCR102C/YNL134C/YLR460C |
| A3 (0034) | ALL (Torulaspora sp.) | Sugar (or other) transporter, probably hexose transporter, or plasma membrane high glucose sensor | RGT2/HXT10/HXT5/STL1/SNF3 |
| A4 (0045) | ALL (Torulaspora sp.) | Aldehyde reductase | YDR541C/GRE2/ARI1 |
| A5 (0056) | ALL (Torulaspora sp.) | Galactose mutarotase-like, probably UDP-glucose-4-epimerase | GAL10 |
| A6 (0078) | ALL (Torulaspora sp.) | Fungal transcription factor, probably involved in regulating lysine biosynthesis | LYS14 |
| A7 (0089) | ALL (Torulaspora sp.) | Arginase | CAR1 |
| A8 (0100) | ALL (Torulaspora sp.) | Member of the multidrug and toxic compound extrusion (MATE) family, probably Na + -driven multidrug efflux pump | ERC1/YDR338C |
| A9 (0111) | ALL (Torulaspora sp.) | Contains a solute binding domain of nucleobase-cation-symport-1 (NCS1) transporter NRT1-like, probably transporter of thiamine or related compound | THI72/THI7 |
| A10 (0133) | ALL (Torulaspora sp.) | Methyltransferase | COQ5 |
| A11 (0144) | ALL (Torulaspora sp.) | FAD/FMN-containing dehydrogenase, probably 2-hydroxyglutarate transhydrogenase and minor D-lactate dehydrogenase | DLD3/DLD2 |
| A12 (0155) | ALL (Torulaspora sp.) | 2-Nitropropane dioxygenase or nitronate monooxygenase | YJR149W |
| B24 (0056) | AHG (Z. bailii) | Fungal transcription factor | STB4 |
| B25 (0012) | AHG (Z. bailii) | 5-oxoprolinase | OXP1 |
| B26 (0023) | AHG (Z. bailii) | Member of the Major Facilitator Superfamily (MFS), probably sugar phosphate permease (D-galactonate transporter) or high affinity nicotinic acid plasma membrane permease | TNA1 |
| B27 (0034) | AHG (Z. bailii) | Flocculation or pseudohypha formation, contains a Flo11 domain | FLO11 |
| B28 (0045) | AHG (Z. bailii) | Contains a fungal specific transcription factor domain | No ortholog found |
| C42 (6480) | BSS (T. microellipsoides) | Contains a fungal transcription factor domain | PUT3 |
| C43 (6491) | BSS (T. microellipsoides) | Member of the Major Facilitator Superfamily (MFS), probably allantoate transporter | SEO1 |
| C44 (6502) | BSS (T. microellipsoides) | Contains a solute binding domain of solute carrier families 5 and 6-like, probably related to amino acid transporter. Oligopeptide transporter. | FOT1/AVT5/AVT6 |
| C45 (6524) | BSS (T. microellipsoides) | Superoxide dismutase, probably mitochondrial manganese superoxide dismutase | SOD2 |
| C46 (6535) | BSS (T. microellipsoides) | Ferric reductase with similarity to Fre2p | FRE7 |
| C47 (6546) | BSS (T. microellipsoides) | Mannitol-1-phosphate/altronate dehydrogenase or mannitol dehydrogenase | DSF1 |
| C48 (6557) | BSS (T. microellipsoides) | Sugar transporter, probably hexose transporter or transmembrane polyol transporter | HXT13/HXT17/HXT15/HXT16/GAL2 |
| C49 (6568) | BSS (T. microellipsoides) | Plasma membrane protein, probably ammonium permease | ATO3 |
| C50 (6579) | BSS (T. microellipsoides) | Galactose mutarotase-like, probably aldose 1-epimerase or UDP-glucose-4-epimerase | YNR071C/YHR210C/GAL10 |
| C51 (6612) | BSS (T. microellipsoides) | Short-chain dehydrogenase/reductase, probably NADP-dependent mannitol dehydrogenase or peroxisomal 2,4-dienoyl-CoA reductase | SPS19 |
| C52 (6623) | BSS (T. microellipsoides) | Threonine dehydrogenase or related Zn-dependent dehydrogenase, sorbitol or xylitol dehydrogenase | XDH1/SOR2/SOR1 |
| C53 (6634) | BSS (T. microellipsoides) | Sugar (or other) transporter, fructose symporter (fructose/H + symporter) or myo-inositol transporter | FSY1/ITR2/ITR1/CIN10/HXT17/HXT13 |
| C54 (6645) | BSS (T. microellipsoides) | Y’ element-encoded DNA helicase | YRF1-7/YRF1-6/YRF1-1 |
| C55 (6656) | BSS (T. microellipsoides) | Y’ element-encoded DNA helicase | YRF1-7/YRF1-6/YRF1-1 |
∗ORF order according to the “1002 yeast genomes project” information and annotation name according to the EC1118 strain genome.