FIGURE 1.

Schematic representation of protein self-assembly through designed supramolecular interactions and their biofunctionalization. Receptor-ligand recognition with native pocket and artificial pocket, reproduced with permission from Hou et al. (2013) and Li X.M. et al. (2019), respectively; Electrostatic interactions into anisotropic and isotropic structures, reproduced with permission from Sun et al. (2015) and Chakraborti et al. (2019), respectively; Metal-coordination via tags fusion, reproduced with permission from Bai et al. (2013), or metal-template-mediated reconstruction; Non-specific interaction networks through recreate interfaces or amphiphiles, reproduced with permission from Xu et al. (2019).