Cumulative distribution of gene expression for genes in regions with CNAs between any two samples The X-axis denotes the gene expression level (read counts) on the log2 scale, and the Y-axis denotes the cumulative proportion of gene expression. The P values were derived from the one-sided Kolmogorov−Smirnov test. Genes showing absolute copy number differentiation between the compared samples were used to plot the cumulative distributions. A.−F. Cumulative distribution of the expression of genes located in regions of copy number loss for pair-wise comparisons, Pa vs. Pb, Ra vs. Pa, Ra vs. Pb, Ra vs. Rb, Rb vs. Pa, and Rb vs. Pb. G.−L. Cumulative distribution of the expression of genes located in regions of copy number gains for pair-wise comparisons, Pa vs. Pb, Ra vs. Pa, Ra vs. Pb, Ra vs. Rb, Rb vs. Pa, and Rb vs. Pb.