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. 2020 Apr 23;106(5):717–725. doi: 10.1016/j.ajhg.2020.04.001

Figure 4.

Figure 4

CDK19 Is Localized to the Perinuclear Space and Cytoplasm of Most Neurons but Expressed in the Nucleus in a Few Neurons

(A) Localization of CDK19 in humanized flies (elav > Cdk8 RNAi; UAS-CDK19 reference). Dashed boxes indicate the region that are magnified in images below. White arrow indicates the neuron that expresses CDK19 in nucleus. Scale bar: 10 μm.

(B) Localization of variant CDK19 in the flies (elav > Cdk8 RNAi; UAS-CDK19 p.Thr196Ala).

(C) Localization of variant CDK19 in the flies (elav > Cdk8 RNAi; UAS-CDK19 p.Tyr32His). Scale bar: 10 μm.