Table 1.
Glutathione-related sex differences in humans and animal models.
| Parameter | Tissue | Species/Animal Model | Condition | Difference | References |
|---|---|---|---|---|---|
| GSH concentration | erythrocytes | human | AD | F > M | [66] |
| GSH/GSSG ratio | Liver mitochondria | Wistar and Goto-Kakizaki rat | Type2 diabetes | F > M | [22] |
| GCL activity | liver | C57BL/6 mice | Liver damage | F > M | [84] |
| GGT activity | serum | human | Arterial tiffness | M > F | [54] |
| GR activity | liver | Fischer 344 rat | Aging | M > F | [92] |
| GR activity | brain | Sprague–Dawley rats | Developmental disorders | M > F | [28] |
| GR activity | liver | sheep | Fetuses | M > F | [1] |
| GR activity | endothelial cells | human | TBH challenge | F > M | [63] |
| GR activity | erythrocytes | human | Preterm infants | F > M | [41] |
| GPx activity | heart | rat | Castration | M > F | [11] |
| GPx activity | erythrocytes | human | Premenopausal period | F > M | [82] |
| GPx activity | heart | rat | Castration | M > F | [11] |
| GPx activity | erythrocytes | human | Preterm infants | F > M | [41] |
| GPx3 activity | kidney | mice | Orchidectomy | F > M | [91] |
| GST activity | brain | rat, vulture | Postnatal development | F > M | [20] |
| GST activity | brain | pigeon, kite, crow | Postnatal development | M > F | [20] |
| GST activity | brain | chicken | Healthy | M > F | [83] |
| GST activity | kidney | chicken | Healthy | F > M | [83] |
| seGPx activity | lung | human | Newborns | F > M | [116] |