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. Author manuscript; available in PMC: 2020 May 11.
Published in final edited form as: Am Psychol. 2017 May-Jun;72(4):326–338. doi: 10.1037/amp0000042

Table 1.

Results of intellectual functioning from meta-analyses of children with selected chronic health conditions.

Health Condition Number of Studies Domains Comparison Group Effect Size (d or g) Effect Size (IQ points)

Type 1 diabetes (Naguib et al., 2009) 24 PIQ Healthy control d = −0.18 −2.7
VIQ Healthy control d = −0.15 −2.25
FSIQ Healthy control d = −0.14 −2.1

Congenital heart defects (HLHS) (Karsdorp et al., 2007) 4 PIQ Normative sample g = −0.88 −13.2
VIQ Normative sample g = −0.43 −6.45
FSIQ Normative sample g = −0.82 −12.3

Congenital heart disease (TGA) (Karsdorp et al., 2007) 11 PIQ Normative sample g = −0.29 −4.35
VIQ Normative sample g = −0.05 −0.75
FSIQ Normative sample g = −0.14 −2.1

Sickle cell disease (Schatz et al., 2002) 18 FSIQ Healthy control g = −0.31 −4.3

Leukemia (Campbell et al., 2009) 28 PIQ Healthy control g = −0.71 −10.65
VIQ Healthy control g = −0.58 −8.7
FSIQ Healthy control g = −0.66 −9.9

Brain tumors (Robinson et al., 2010) 39 PIQ Normative sample g = −0.88 −13.2
VIQ Normative sample g = −0.74 −11.1
FSIQ Normative sample g = −0.83 −12.45

Traumatic Brain Injuries (mild) (Babikian & Asarnow, 2009) 28 PIQ Healthy control g = −0.22 −3.3
VIQ Healthy control g = −0.14 −2.1
FSIQ Healthy control g = −0.21 −3.15

Traumatic Brain Injuries (moderate) (Babikian & Asarnow, 2009) 28 PIQ Healthy control g = −0.83 −12.45
VIQ Healthy control g = −0.67 −10.05
FSIQ Healthy control g= −0.92 −13.8

Traumatic Brain Injuries (severe) (Babikian & Asarnow, 2009) 28 PIQ Healthy control g = −0.89 −13.35
VIQ Healthy control g = −0.52 −7.8
FSIQ Healthy control g = −0.79 −11.85