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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: FASEB J. 2019 Dec 4;34(1):1679–1694. doi: 10.1096/fj.201900567RR

FIGURE 4.

FIGURE 4

GW2580 attenuates MPTP-induced tissue inflammatory response without reducing anti-inflammatory mRNA levels. A, Gene expression analysis of Csf1r, Csf1, and Il-34 in the striatum 2 days following MPTP and GW2580 treatment. B, Gene expression analysis of the pro-inflammatory factors Nos2, gp91phox, Il-6, and Il-1b in the striatum 2 days following MPTP and GW2580 treatment. C, Gene expression analysis of the anti-inflammatory factors Arginase-1, Ym1, Nrf2, and Mrc1 in the striatum 2 days following MPTP and GW2580 treatment. All data are represented as mean ± SEM; n = 3–4 animals per group; *P < .05, **P < .01, ns = not statistically significant