Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Competition assays with dxCas9 and dCas9–NG. A, structures of competitor DNA probes. The probes bore 2-bp segments upstream of PAM sequences (highlighted in yellow) that were complementary to gRNA. B and C, effect of competitor probes bearing indicated PAM sequences on the kinetics of dxCas9–gRNA (B) and dCas9–NG–gRNA (C) binding to beacon. The concentrations of competitor DNA probes were 200 and 40 nm in experiments shown in B and C, respectively.
