Phylogenetic analysis of photosensory core modules of TCCP, Cph1/CphA, and BphP/CphB family representatives supports a monophyletic TCCP lineage in cyanobacteria. The TCCP family consisting of NpTCCP (NpF1183) from N. punctiforme ATCC 29133 (15), orthologues ToTCCP from Tolypothrix PCC7910 (Tpr0787), ScTCCP from Scytonema PCC10023 (Spr6432), and GlTCCP from Gloeocapsa PCC7513 (Gpr2095) studied here (indicated with arrows), comprise a monophyletic clade distinct from Cph1/CphA and BphP/CphB cyanobacterial phytochrome families. Noncyanobacterial BphPs are included as an outgroup. Detailed sequence names, accessions, and sequence alignments are included as in Data File S1.