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Immunoelectron microscopy of brain lysates from homozygous M83 mice following sucrose gradient fractionation. A, immunoelectron microscopy of fractionated brain lysates from homozygous, symptomatic mice transgenic for human A53T α-synuclein (line M83) with anti-α-synuclein pS129 antibody. The measured filament lengths (20, 30, 40, 50%, and pellet) are shown (n = 15). Scale bar, 200 nm.
