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. 2020 May 4;11:549. doi: 10.3389/fphar.2020.00549

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Copyright © 2020 Dong, Yan, Zhao, Lin, Lin, Ding, Liu, Ren, Xing and Ji

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GBFXD increased the levels of total SCFAs in serum, and acetate and propionate levels in the feces. (A–C) Acetate, Propionate, and Butyrate concentrations in feces. (D) Total SCFAs concentrations in serum. Data are shown as mean ± SD, n = 5 mice per group. Data in (A–C) were analyzed by one-way ANOVA with Dunnett’s post hoc tests for multiple comparisons. Data in (D) were analyzed by Kruskal-Wallis test with Dunn’s multiple comparisons. *P < 0.05, **P < 0.01, ***P < 0.001 compared to Model group. ns means no statistical significance.