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. 2020 May 4;11:311. doi: 10.3389/fphys.2020.00311

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Copyright © 2020 Meng, Chen, Lin, Wang, Xu and Weng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Exercise reversed the alterations in gut microbiota in response to cold exposure. (A) Relative abundance at the phylum level. (B) Comparison of phylum-level proportional abundance in feces up to 35 days in response to cold exercise, cold exposure alone, exercise alone, or in control rats. The blue color denotes an increase, and the red color denotes a decrease. +P < 0.1; *P < 0.05; **P < 0.01. (C) Richness is represented as the proportion of operational taxonomic units (OTUs) classified at the phylum level. (D) Box plots showing the transformed relative abundance change in representative genera following intervention selected for the first 15 most important genera.