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. 2020 Mar 27;2(1):vdaa042. doi: 10.1093/noajnl/vdaa042

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© The Author(s) 2020. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 5. — Gene set enrichment analysis (GSEA) of high versus low mutation load in LGG-mIDH-A and LGG-mIDH-O. (A and C) Cytoscape map visualization of the positive (red) and negative (blue) enriched GO groups in high versus low mutation load in LGG-mIDH-A (LGG-mIDH-A^highN = 189, LGG-mIDH-A^lowN = 63) (A) and LGG-mIDH-O (LGG-mIDH-O^highN = 74, LGG-mIDH-O^lowN = 95) (C). (B and D) Enrichment plots of the top significantly altered GO in the high versus low mutation load in LGG-mIDH-A and LGG-mIDH-O.