Skip to main content
. 2020 Feb 28;2(1):vdaa028. doi: 10.1093/noajnl/vdaa028

Figure 4.

Figure 4

Reduced vascular function in normal-appearing brain is more pronounced in a patient with pre-SRS ECOG status >0 compared to 0. Mean ± SEM of normalized (n) metrics relative to pre-SRS (%) in normal-appearing brain tissue in LowDose on a logarithmic scale for patients with pre-SRS Eastern Cooperation Oncology Group (ECOG) status of 0 (gray) and >0 (brown). (A) Transiently reduced nMicro-vascular blood volume (CBV) and (B) nMicro-vascular blood flow (CBF) in patients with pre-SRS ECOG status >0 compared to increased nMicro-CBV at 9–12 months post-SRS in patients with pre-SRS ECOG status 0. (C) Transient increase in nMean vessel calibers was higher in patients with pre-SRS ECOG status >0 compared to 0. The number of patients (N) with available data in each group is shown in the legend box. P values from Mann–Whitney U test (between groups) and the Wilcoxon Signed-Rank test (relative to pre-SRS).