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. 2019 May 28;1(1):vdz004. doi: 10.1093/noajnl/vdz004

Fig. 3.

Fig. 3

Effects of PI3K and mitogen-activated protein kinase (MEK) inhibition. Representative blots for SU-DIPG-IV cells treated with ZSTK474, trametinib, or their combination (A). Semi-quantification of pAKT (B) and pERK (C) as protein expression fold-change over 0.1% DMSO vehicle. Representative blots for SU-DIPG-XIII cells treated with ZSTK474, trametinib, or their combination (D). Semi-quantification of pAKT (E) and pERK (F) as protein expression fold-change over 0.1% DMSO vehicle. One-way t tests were conducted against fold-change of 1, *P < .05, **P < 0.01, ***P < .001. Error bars SEM.