Structures of representative small proteins. Structures of AcrZ, KdpF, CydX, and CydH (red) in association with the AcrB multidrug efflux pump (PDB 4C48 [84]), Kdp potassium transporter (PDB 5MRW [69]), and cytochrome bd-I oxidase (PDB 6RKO [80]), respectively. The approximate position of the membrane is indicated by shading.