Table 1.
Summary of Patient Data by Glioma Molecular Subtype and Sex
| Female | Male | P-value | |||
|---|---|---|---|---|---|
| IDHwt GBM | N | 31 | 44 | ||
| Mean age in yrs (SD) | 65.26 (11.89) | 63.00 (8.75) | .35a | ||
| Age range | 39–85 | 47–83 | |||
| Adjusted median overall survivalc (months) [95% CI] | 8.3 [6.6–15.3] | 5.4 [4.7–12.0] | .01b | ||
| Living (%) | No | 31 (100.00) | 44 (100.00) | NA | |
| IDHwt non-GBM | N | 42 | 52 | ||
| Mean age in yrs (SD) | 49.18 (14.31) | 53.83 (14.89) | .14a | ||
| Age range | 24–74 | 21–87 | |||
| Adjusted median overall survivalc (months) [95% CI] | 21.2 [16.8–60.0] | 21.0 [16.4–27.2] | .01b | ||
| Living (%) | No | 22 (52.4) | 32 (61.5) | .50d | |
| Yes | 20 (47.6) | 20 (38.5) | |||
| IDHmut-codel non-GBM | N | 78 | 94 | ||
| Mean age in yrs (SD) | 46.44 (13.06) | 44.12 (12.50) | .24a | ||
| Age range | 20–74 | 17–75 | |||
| Adjusted median overall survivalc (months) [95% CI] | NA [NA–NA] | NA [68.4–NA] | <.01b | ||
| Living (%) | No | 7 (9.0) | 10 (10.6) | .91d | |
| Yes | 71 (91.0) | 84 (89.4) | |||
| IDHmut-non-codel non- GBM | N | 109 | 137 | ||
| Mean age in yrs (SD) | 38.65 (10.95) | 37.23 (10.88) | .31a | ||
| Age range | 18–73 | 14–70 | |||
| Adjusted median overall survivalc (months) [95% CI] | 60 [60–NA] | 368 [60–NA] | .40b | ||
| Living (%) | No | 22 (20.2) | 21 (15.3) | .41d | |
| Yes | 87 (79.8) | 116 (84.7) |
Two IDHwt GBM patients, 1 male and 1 female, were missing 1p/19q co-deletion status data. Age data were missing for 3 females and 4 males in the IDHwt non-GBM subtype.
a P-value from t test.
b P-value from log-rank test.
cAdjusted for by age.
d P-value from chi-square test.