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. 2019 May 28;1(1):vdz003. doi: 10.1093/noajnl/vdz003

Fig. 2.

Fig. 2

Diagrams summarizing the mutation analysis of the PIK3CA/AKT1 pathway in meningiomas developed on cyproterone acetate (CPA). (A) Schematic diagram depicting the approximate location of CPA meningiomas in the skull base. PIK3CA mutant, AKT1 mutant, AKT1 wild-type and PIK3CA wild-type with copy number gain and PIK3CA wild-type and AKT1 wild-type with normal copy number are distinguished by different colored spots. (B) Diagram showing the distribution of pathogenic mutations of AKT1 and PIK3CA genes in the CPA cohort (1) compared to the control cohort (2).