Table 1.
Clinical Information on Patients in the Cyproterone Acetate (CPA) Cohort. CPA Cohort Consisted of 29 Female Patients and Only 1 Male Patient
| Age (years) | Sex | CPA indication | CPA daily dose (mg/d) | CPA exposure (years) | Symptoms appeared under CPA | Radio-clinical evolution after CPA discontinuation | |
|---|---|---|---|---|---|---|---|
| Patient 1 | 63 | M | Prostate cancer | 100 | <10 | Left visual loss, memory disorders | Improvement |
| Patient 2 | 33 | F | Hirsutism | 25 | >10 | Right vestibular syndrom, right hypoacusis | Stable |
| Patient 3 | 49 | F | Hirsutism | 25 | >10 | Left visual loss | Improvement |
| Patient 4 | 48 | F | Hirsutism | 25 | >10 | Right visual loss | Improvement |
| Patient 5 | 52 | F | Hirsutism | 25 | >10 | Left visual loss | Improvement |
| Patient 6 | 29 | F | Hirsutism | 25 | <10 | Right V1, V2 and V3 deficit, right vestibular syndrom | Stable |
| Patient 7 | 52 | F | Hirsutism | 25 | >10 | Right visual loss | Improvement |
| Patient 8 | 29 | F | Hirsutism | 25 | >10 | Right visual loss | Improvement |
| Patient 9 | 64 | F | Hirsutism | 25 | >10 | Left visual loss | Stable |
| Patient 10 | 49 | F | Hirsutism | 25 | >10 | Right visual loss | Improvement |
| Patient 11 | 50 | F | Hirsutism | 25 | >10 | Left visual loss | Improvement |
| Patient 12 | 53 | F | Hirsutism | 25 | >10 | Left visual loss | Stable |
| Patient 13 | 38 | F | Hirsutism | 25 | >10 | Bilateral visual loss | Stable |
| Patient 14 | 62 | F | Hirsutism | 25 | <10 | Right visual loss | Improvement |
| Patient 15 | 68 | F | Hirsutism | 25 | >10 | Right visual loss | Improvement |
| Patient 16 | 47 | F | Hirsutism | 25 | >10 | Left exophtalmia, left visual loss | Improvement |
| Patient 17 | 49 | F | Hirsutism | 25 | >10 | Right visual loss | Improvement |
| Patient 18 | 51 | F | Hirsutism | 25 | >10 | Frontal swelling | Improvement |
| Patient 19 | 33 | F | Hirsutism | 25 | >10 | Frontal swelling | Improvement |
| Patient 20 | 47 | F | Hirsutism | 25 | >10 | Right visual loss | Stable |
| Patient 21 | 43 | F | Hirsutism | 25 | >10 | Right visual loss | Stable |
| Patient 22 | 37 | F | Hirsutism | 25 | >10 | Left visual loss | Stable |
| Patient 23 | 68 | F | Hirsutism | 25 | >10 | Left visual loss | Improvement |
| Patient 24 | 50 | F | Hirsutism | 25 | >10 | Left visual loss | Improvement |
| Patient 25 | 67 | F | Hirsutism | 25 | >10 | Left visual loss | Improvement |
| Patient 26 | 56 | F | Hirsutism | 25 | <10 | Frontal syndrom, phasic disorders | Improvement |
| Patient 27 | 47 | F | Hirsutism | 25 | >10 | Left visual loss | Improvement |
| Patient 28 | 49 | F | Hirsutism | 25 | >10 | Left visual loss | Stable |
| Patient 29 | 50 | F | Hirsutism | 25 | >10 | Right visual loss | Improvement |
| Patient 30 | 58 | F | Hirsutism | 25 | >10 | Bilateral ophtalmoplegia | Improvement |