Figure 2.

The first image is an axial image from the computed tomography (CT) simulation study of case 2, obtained 9 days before start of stereotactic body radiation therapy (SBRT) to the left upper lobe lesion (not shown). The second image is the cone beam CT (CBCT) taken before the first fraction of treatment. On day 2, the patient began to experience increasing shortness of breath and cough. On the third fraction of treatment, peripheral ground glass opacities were seen in the right upper lobe, out of the treatment field, which were new compared with the first 2 images shown here.