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. 2020 May 6;14:1229–1236. doi: 10.2147/OPTH.S216907

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© 2020 Kusuhara and Nakamura.

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Schematic illustration of the Rho/ROCK signaling pathway in trabecular meshwork cells.

Abbreviations: RhoGEF, Rho guanine nucleotide exchange factor; ROCK, Rho-associated coiled-coil-containing protein kinase; MLC, myosin light chain; LIMK, Lin-1/Isl-1/Mec-3 kinase; ECM, extracellular matrix.