Figure 2.

Associations of baseline plasma APOC-III levels with changes in CSF AD pathologies. The tertiles of plasma APOC-III were associated with changes in CSF Aβ42 (A), but not t-tau (B) or p-tau (C). Specifically, the CSF Aβ42 reduction for individuals in the highest APOC-III tertile was significantly slower compared with those in the middle (the middle tertile of APOC-III – the highest tertile of APOC-III: estimate = −2.151, SE = 0.909, p = 0.0484), whereas no other pairwise difference was found to be statistically significant (all p > 0.05).

Abbreviations: APOC-III, apolipoprotein C-III; Aβ42, β-amyloid 42; t-tau, total tau; p-tau, phosphorylated tau.