Table 4.

Comparison of scan types (ssDTI versus rsDTI) in healthy controls and NF1 patients with and without visual symptoms. Data reported as mean ± standard error of mean

	Scan type	Tract count	Tract length	Tract volume	FA	MD	AD	RD
Healthy control	ssDTI	1182.8 ± 145.9	6.8 ± 1.5	686.6 ± 178.7	0.29 ± 0.02	1.92 ± 0.13	2.42 ± 0.13	1.68 ± 0.12
	rsDTI	1812.8 ± 539.5	10.0 ± 5.1	709.8 ± 198.6	0.41 ± 0.02*	1.77 ± 0.20	2.43 ± 0.24	1.44 ± 0.18
	p value	0.221	0.222	0.652	0.001	0.344	0.974	0.131
NF_1 + no visual	ssDTI	1073.3 ± 291.4	5.1 ± 0.8	449.5 ± 88.2	0.27 ± 0.01	2.09 ± 0.10	2.57 ± 0.11	1.85 ± 0.10
	rsDTI	2289.3 ± 265.0*	7.2 ± 1.2	1015.5 ± 149.3*	0.39 ± 0.02*	1.58 ± 0.10*	2.17 ± 0.13*	1.28 ± 0.09*
	p value	0.001	0.356	< 0.001	< 0.001	< 0.001	0.016	< 0.001
NF_1 + Visual	ssDTI	603.8 ± 235.5	5.8 ± 1.3	408.8 ± 158.9	0.31 ± 0.02	1.64 ± 0.09	2.11 ± 0.11	1.40 ± 0.09
	rsDTI	1787.2 ± 421.1*	7.7 ± 1.0	1088.0 ± 138.6*	0.42 ± 0.03*	1.37 ± 0.14	1.91 ± 0.17	1.10 ± 0.13
	p value	0.015	0.390	0.001	0.001	0.099	0.291	0.047

^*Significant rsDTI vs. ssDTI within patient groups