Table 5.

Comparison of NF1 subjects with and without prior or concurrent chemotherapy. Data reported as mean ± standard error

	Scan type	Tract count	Tract length	Tract volume	FA	MD	AD	RD
NF_1 No Chemo	ssDTI	1069.8 ± 316.8	5.0 ± 0.9	433.0 ± 94.2	0.27 ± 0.01	2.12 ± 0.11	2.60 ± 0.12	1.87 ± 0.10
	rsDTI	2234.3 ± 286.6*	7.04 ± 1.3	1047.3 ± 161.3*	0.40 ± 0.02*	1.55 ± 0.11*	2.15 ± 0.14*	1.25 ± 0.09*
p value		0.003	0.066	< 0.001	< 0.001	< 0.001	0.020	< 0.001
NF_1 + Chemo	ssDTI	676.9 ± 212.0	5.72 ± 1.1	443.1 ± 138.6	0.31 ± 0.02	1.66 ± 0.08	2.14 ± 0.09	1.43 ± 0.08
	rsDTI	1937.4 ± 386.3*	7.8 ± 0.85	1031.9 ± 129.7*	0.41 ± 0.02*	1.43 ± 0.13	2.00 ± 0.16	1.16 ± 0.12
p value		0.032	0.050	0.024	0.002	0.166	0.411	0.089

^*Significant rsDTI vs. ssDTI within patient groups