Table 4.
Unadjusted and Adjusted PRa for modified Ferriman-Gallwey score ≥8 vs <8 restricted to women without a PCOS diagnosis, n=4,800
| No. of women | Unadjusted | Adjusted | |||
|---|---|---|---|---|---|
| PR | 95% CI | PR | 95% CI | ||
| Age at menarche, years | |||||
| <12 | 1,337 | 1.34 | 1.17, 1.54 | 1.22 | 1.07, 1.40 |
| 12-13 | 2,492 | 1.00 | Ref | 1.00 | Ref |
| 14 | 562 | 0.94 | 0.76, 1.17 | 1.00 | 0.81, 1.24 |
| ≥15 | 409 | 0.95 | 0.75, 1.21 | 1.00 | 0.78, 1.27 |
| Time to menstrual regularity, years | 3,505 | 1.06 | 1.02, 1.09 | 1.05 | 1.02, 1.08 |
| Cycle regularity | |||||
| Regular | 3,741 | 1.00 | Ref | 1.00 | Ref |
| Irregular | 1,059 | 1.61 | 1.42, 1.84 | 1.47 | 1.29, 1.68 |
| Number of cycles (periods/year) | 4,800 | 0.94 | 0.92, 0.97 | 0.96 | 0.93, 0.98 |
| Cycle length, daysb | 3,741 | 1.02 | 0.99, 1.05 | 1.02 | 1.00, 1.04 |
| Cycle length, daysb | |||||
| <28 | 1,036 | 1.00 | Ref | 1.00 | Ref |
| 28-35 | 2,643 | 1.20 | 1.00, 1.43 | 1.21 | 1.01, 1.45 |
| ≥36 | 62 | 1.45 | 0.85, 2.47 | 1.35 | 0.79, 2.31 |
| Bleed length, days | |||||
| <3 | 189 | 1.00 | Ref | 1.00 | Ref |
| 3-4 | 2,295 | 1.37 | 0.92, 2.03 | 1.31 | 0.89, 1.93 |
| 5-6 | 1,959 | 1.43 | 0.96, 2.12 | 1.36 | 0.92,2.01 |
| ≥7 | 357 | 2.03 | 1.33, 3.11 | 1.76 | 1.16, 2.67 |
| Bleed heaviness | |||||
| Light | 879 | 0.91 | 0.76, 1.09 | 0.94 | 0.78, 1.12 |
| Moderate | 2,567 | 1.00 | Ref | 1.00 | Ref |
| Moderate/heavy | 1,129 | 1.20 | 1.04,1.39 | 1.13 | 0.98, 1.30 |
| Heavy | 225 | 1.58 | 1.25, 2.00 | 1.37 | 1.08, 1.73 |
a
=adjusted for cycle at study entry, smoking status (current vs not current), MET hours of physical activity per week (<10, 10-19, 20-39,≥40), age (<25, 25-29, 30-34, ≥35 years), BMI (<18, 18-24, 25-29, 30-34, ≥35 kg/m2), caffeine (<100, 100-199, 200-299, >300 mg/day), last form of birth control being hormonal (yes vs no), alcohol intake per week (0, 1-6, 7-13, ≥14 drinks/week)
b
=among those with regular cycles (3,741)