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Kinetics of development of antibody responses to OV-16, OVOC3261, and OVOC10469 in nonhuman primates (NHP). The kinetics of IgG (dotted) and IgG4 (solid) responses to OV-16 (red), OVOC3261 (blue), and OVOC10469 (green) in serum of 4 experimentally infected NHPs (A–D) by luciferase immunoprecipitation system. The values on the y-axis denote the net relative light units (RLU). The vertical violet dotted line denotes the time of appearance of skin microfilariae.
