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. 2020 Jan 4;221(11):1855–1863. doi: 10.1093/infdis/jiz693

Table 2.

Inverse Variance Weighted Simple Linear Regression Models of Each Predictor on GII.4 Proportion

Predictor R2 β 95% CI
Secretor Proportion 0.05 1.17 0.69–1.64
Study Type 0.02
 Outbreaks 0.00 Reference
 Inpatient Cases 0.03 −0.06 to 0.11
 Outpatient Cases 0.00 −0.10 to 0.11
 Inpatient and Outpatient Cases −0.03 −0.12 to 0.06
 Community Cases −0.10 −0.23 to 0.04
 Mixed Setting 0.06 −0.03 to 0.14
 Not Specified 0.12 −0.10 to 0.34
Age Category 0.02
 ≤5 Years 0.00 Reference
 >5 Years 0.05 −0.11 to 0.20
 Mixed 0.11 0.03–0.19
Pandemic Variant Period 0.24
 2012–2017 0.00 Reference
 1994–2001 −0.12 −0.22 to −0.02
 2002–2003 0.15 0.03–0.27
 2004–2005 0.29 0.17 to 0.42
 2006–2008 0.32 0.26–0.39
 2009–2011 0.12 0.01–0.23
 Multiple Periods 0.13 0.06–0.20
WHO Region 0.05
 Western Pacific 0.00 Reference
 Africa −0.18 −0.46 to 0.09
 Americas 0.04 −0.03 to 0.11
 Southeast Asia −0.11 −0.36 to 0.14
 Europe 0.11 0.04 to 0.18
 Eastern Mediterranean −0.36 −0.61 to −0.10
HDI 0.10 1.01 0.71–1.31
Detection Method 0.00
 RT-PCR 0.00 Reference
 Other 0.00 −0.14 to 0.15
 Unknown 0.06 −0.05 to 0.17
Typing Region 0.04
 ORF1 0.00 Reference
 ORF2 −0.11 −0.18 to −0.04
 ORF1 and ORF2 −0.03 −0.13 to 0.06
 Overlap Only −0.01 −0.12 to 0.10
 Unknown 0.03 −0.07 to 0.14

Abbreviations: CI, confidence interval; GII.4, genogroup 2 type 4; HDI, Human Development Index; ORF, open reading frame; RT-PCR, reverse transcription polymerase chain reaction; WHO, World Health Organization.