Predictiveness curves for risk of adverse pathology (AP) at 2 years, in which the cumulative percentage of the cohort at risk is plotted against the risk estimated from models. The solid gray line shows the prevalence of AP. The dashed black line shows a risk threshold of ≥ 70% for high risk of AP with triangles at the percent of the population stratified as high risk at that threshold. For well-calibrated models, the model with a curve further away from the prevalence line may be helpful for more individuals in making an unequivocal decision on active surveillance (AS). GG, Gleason Grade Group; GPS, Genomic Prostate Score; PSA, prostate-specific antigen.