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. 2020 Apr 15;6(5):e549. doi: 10.1097/TXD.0000000000000995

FIGURE 3.

FIGURE 3.

MiR-126 and target levels in HMVCECs treated with immunosuppressive agents. A, MiR-126-3p levels are not influenced by the administration of immunosuppressive agents (P = 0.112 for trend, n = 5–6 per group) although there is a trend toward higher levels of miR-126-3p in mycophenolate-treated cells. B, miR-126-5p are altered by the administration of immunosuppressants (P = 0.054 for trend, n = 5–6 per group) again with higher levels in mycophenolate-treated cells. C, PIK3R2 levels are lower in all groups treated with immunosuppressive agents, especially in the mycophenolate group (P = 0.044 for trend, n = 5–6 per group); D, SPRED1 levels are especially lower in methylprednisolone-treated cells and not in the other groups (P = 0.053 for trend, n = 5–6 per group). *P < 0.05 vs control, ANOVA with post-hoc correction. HMVCECs, human microvascular cardiac endothelial cells; miR, microRNA.