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. 2020 May 11;15(5):e0232703. doi: 10.1371/journal.pone.0232703

Table 3. Bivariable logistic regression analysis of factors associated with adherence among HIV/AIDS patients at Nekemte referral hospital, West Ethiopia, 2019 (n = 305).

Variables Adherence COR (95%) CI P value
Adherent (%) Not adherent (%)
Sex
Male 97 (69.3%) 43 (30.7%) 1
Female 126 (76.4%) 39 (23.6%) 1.43 (0.86, 2.38) 0.16
Age (years)
18–28 69 (66.3%) 35 (33.7%) 2.36 (1.04, 5.36) 0.04*
29–38 78 (73.6%) 28 (26.4%) 1.57 (0.73, 3.40) 0.24
39–48 36 (78.3%) 10 (21.7%) 1.08 (0.42, 2.73) 0.86
>48 40 (81.6%) 9 (18.4%) 1
Marital status
Married 81 (80.2%) 20 (19.8%) 1
Single 92 (73.0%) 34 (27.0%) 0.66 (0.35, 1.25) 0.20
Divorced 26 (65.0%) 14 (35.0%) 0.45 (0.20, 1.03) 0.06
Widowed 24 (63.2%) 14 (36.8%) 0.42 (0.18, 0.96) 0.04*
Ethnicity
Oromo 134 (72.8%) 50 (27.2%) 1
Amhara 61 (75.3%) 20 (24.7%) 1.13 (0.62, 2.07) 0.67
Tigre 13 (72.2%) 5 (27.8%) 0.97 (0.32, 2.86) 0.95
Gurage 9 (75.0%) 3 (25.0%) 1.11(0.29, 4.30) 0.87
Others 6 (60.0%) 4 (40.0%) 0.56 (0.15, 2.06) 0.38
Educational status
No formal education 11 (55.0%) 9 (45.0%) 0.40 (0.13, 1.20) 0.10
Primary school (1–8) 73 (66.4%) 37 (33.6%) 0.65 (0.31, 1.38) 0.26
Secondary school (9–12) 100 (81.3%) 23 (18.7%) 1.44 (0.66, 3.14) 0.34
College and above 39 (75.0%) 13 (25.0%) 1
Residence
Urban 62 (68.9%) 28 (31.1%) 1
Rural 161 (74.9%) 54 (25.1%) 1.34 (0.78, 2.31) 0.28
Occupation
Government employee 28 (80.0%) 7 (20.0%) 1
Private employee 72 (75.0%) 24 (25.0%) 0.75 (0.29, 1.93) 0.55
Farmer 56 (67.5%) 27 (32.5%) 0.51 (0.20, 1.33) 0.17
Merchant 58 (71.6%) 23 (28.4%) 0.63 (0.24, 1.64) 0.34
Others 9 (90.0%) 1 (10.0%) 2.25 (0.24, 20.83) 0.47
Income
<500 EB 35 (56.5%) 27 (43.5%) 0.23 (0.07, 0.67) 0.008*
500–1000 EB 41 (73.2%) 15 (26.8%) 0.48 (0.15, 1.49) 0.21
1001–1500 EB 51 (69.9%) 22 (30.1%) 0.41 (0.14, 1.21) 0.10
1501–2000 EB 68 (84.0%) 13 (16.0%) 0.93 (0.30, 2.86) 0.90
>2000 EB 28 (84.8%) 5 (15.2%) 1
Number of pills taken in a day
2 tablets 114 (75.5%) 37 (24.5%) 1
3 tablets 52 (72.2%) 20 (27.8%) 0.84 (0.44, 1.59) 0.60
4 tablets 43 (69.4%) 19 (30.6%) 0.73 (0.38, 1.41) 0.35
>4 tablets 14 (70.0%) 6 (30.0%) 0.75 (0.27, 2.11) 0.59
Living companion
Yes 178 (88.1%) 24 (11.9%) 9.55 (5.36, 17.0) 0.000*
No 45 (43.7%) 58 (56.3%) 1
CD4 cell
<200 31 (73.8%) 11 (26.2%) 1.40 (0.35, 5.62) 0.62
200–500 100 (71.4%) 40 (28.6%) 1.25 (0.35, 4.38) 0.72
501–800 84 (75.7%) 27 (24.3%) 1.55 (0.43, 5.57) 0.49
>800 8 (66.7%) 4 (33.3%) 1
HIV stage
Stage I 73 (74.5%) 25 (25.5%) 1
Stage II 88 (75.9%) 28 (24.1%) 1.07 (0.57, 2.00) 0.81
Stage III 31 (64.6%) 17 (35.4%) 0.62 (0.29, 1.31) 0.21
Stage IV 31 (72.1%) 12 (27.9%) 0.88 (0.39, 1.98) 0.76
Side effect of ARV drugs
Yes 44 (38.6%) 70 (61.4%) 1
No 179 (93.7%) 12 (6.3%) 23.7 (11.83, 47.57) 0.000*
Family/social support
Strong 134 (97.1%) 4 (2.9%) 20.79 (6.54, 66.02) 0.000*
Moderate 60 (50.0%) 60 (50.0%) 0.62 (0.31, 1.23) 0.17
Poor 29 (61.7%) 18(38.3%) 1
Perceived stigma
Yes 59 (47.2%) 66 (52.8%) 1
No 164 (91.1%) 16 (8.9%) 11.46 (6.15, 21.35) 0.000*
Substance use
Yes 46 (41.4%) 65 (58.6%) 1
No 177 (91.2%) 17 (8.8%) 14.71 (7.87, 27.47) 0.000*
Disease duration
<1 year 35 (74.5%) 12 (25.5%) 0.87 (0.32, 2.36) 0.79
1–5 years 76 (73.1%) 28 (26.9%) 0.81 (0.34, 1.98) 0.64
6–10 years 82 (71.3%) 33 (28.7%) 0.74 (0.31, 1.74) 0.49
>10 years 30 (76.9%) 9 (23.1%) 1
Treatment duration
<1 year 38 (79.2%) 10 (20.8%) 1
1–5 years 85 (73.3%) 31 (26.7%) 0.72 (0.32, 1.62) 0.42
6–10 years 78 (69.6%) 34 (30.4%) 0.60 (0.27, 1.35) 0.21
>10 years 22 (75.9%) 7 (24.1%) 0.82 (0.27, 2.48) 0.73
Knowledge about HIV and its treatment
Knowledgeable 181 (90.0%) 20 (10.0%) 13.36 (7.29, 24.47) 0.000*
Not knowledgeable 42 (40.4%) 62 (59.6%) 1
Waiting time
<30 minutes 140 (75.3%) 46 (24.7%) 1.32 (0.79, 2.20) 0.28
>/= 30 minutes 83 (69.7%) 36 (30.3%) 1
comorbidity of other chronic illness
Yes 35 (37.6%) 58 (62.4%) 1
No 188 (88.7%) 24 (11.3%) 12.98 (7.14, 23.58) 0.000*
Family disclosure status
Yes 184 (88.9%) 23 (11.1%) 12.10 (6.68, 21.89) 0.000*
No 39 (39.8%) 59 (60.2%) 1

* shows significant at P-value <0.05

COR: Crude Odd Ratio, CI: Confidence Interval