Figure 2.
(A, B) A transthoracic echocardiography (TTE) prior to chemotherapy revealed mitral annular calcification (MAC) (arrow). There were not any apparent tumorous lesions on the mitral valve or other sites. (C, D) A TTE approximately 31 months after MPB therapy and prior to treatment with lenalidomide, dexamethasone and darbepoetin alfa showed MAC (arrow). There were not any obvious tumorous lesions on the mitral valve or other sites. (E, F, G and H) A TTE approximately 18 months after treatment with lenalidomide, dexamethasone and darbepoetin alfa revealed a 20 mm high echoic mass on the mitral valve (arrow). (A, C, E) parasternal long axis view; (B, F, G) apical four-chamber view; (H) apical two-chamber view.
