Table 3. Univariable and multivariable baseline predictors of SVR+ and SVR++ patients with odds ratios (OR) and 95% confidence intervals.
| Univariable ordinal regression | Multivariable ordinal regression | ||||
|---|---|---|---|---|---|
| Variable | Response | OR (95% CI) | Overall P-value | OR (95%CI) | Overall P-value |
| Age (per 10-year increment) | SVR+ | 0.899 (0.466, 1.734) | 0.56 | ||
| SVR++ | 1.410 (0.892, 2.231) | ||||
| Female gender | SVR+ | 1.481 (0.282, 7.766) | 0.90 | ||
| SVR++ | 0.987 (0.254, 3.832) | ||||
| History of hypertension | SVR+ | 1.114 (0.267, 4.652) | 0.25 | ||
| SVR++ | 2.860 (1.081, 7.565) | ||||
| Body mass index (per 5 kg.m-2 increment) | SVR+ | 1.341 (0.616, 2.917) | 0.61 | ||
| SVR++ | 1.445 (0.818, 2.554) | ||||
| ACEI treatment | SVR+ | 0.675 (0.129, 3.542) | 0.90 | ||
| SVR++ | 1.013 (0.261, 3.932) | ||||
| Beta-blocker treatment | SVR+ | 2.096 (0.248, 17.677) | 0.90 | ||
| SVR++ | 1.397 (0.369, 5.290) | ||||
| Peak Creatine Kinase-MB (per 1000 U.L-1) | SVR+ | 1.195 (0.840, 1.699) | 0.63 | ||
| SVR++ | 0.899 (0.672, 1.202) | ||||
| Peak Troponin (μg.L-1) | SVR+ | 1.277 (0.896, 1.821) | 0.61 | ||
| SVR++ | 0.911 (0.677, 1.226) | ||||
| eGFR | SVR+ | 0.893 (0.589, 1.353) | 0.27 | ||
| (per 10 mL.min-1 increment) | SVR++ | 0.724 (0.537, 0.976) | |||
| C-Reactive Protein (mg.L-1) | SVR+ | 1.151 (0.998, 1.327) | 0.36 | ||
| SVR++ | 1.011 (0.864, 1.182) | ||||
| Brain Natriuretic Peptide | SVR+ | 1.021 (0.987, 1.055) | 0.42 | ||
| (per 10 pg.mL-1 increment) | SVR++ | 0.976 (0.938, 1.017) | |||
| NGAL (per 10 ng.mL-1 increment) | SVR+ | 1.236 (1.012, 1.511) | 0.20 | ||
| SVR++ | 1.158 (0.985, 1.361) | ||||
| Renin >15 pg.mL-1 | SVR+ | 1.635 (0.948, 2.821) | 0.75 | ||
| SVR++ | 1.499 (0.971, 2.313) | ||||
| Aldosterone (pg.mL-1) | SVR+ | 3.120 (0.627, 15.531) | 0.90 | ||
| SVR++ | 2.496 (0.841, 7.409) | ||||
| Galectin-3 (ng.mL-1) | SVR+ | 1.204 (1.040, 1.394) | 0.048 | 1.213 (1.040, 1.414) | 0.010 |
| SVR++ | 1.186 (1.057, 1.331) | 1.163 (1.023, 1.323) | |||
| Heart rate (per10 bpm increment) | SVR+ | 1.145 (0.645, 2.032) | 0.90 | ||
| SVR++ | 1.022 (0.663, 1.575) | ||||
| Systolic blood pressure >130 mmHg | SVR+ | 0.412 (0.083, 2.054) | 0.20 | ||
| SVR++ | 2.676 (1.006, 7.120) | ||||
| Diastolic blood pressure >70 mmHg | SVR+ | 0.159 (0.032, 0.793) | 0.048 | ||
| SVR++ | 3.818 (1.047, 13.921) | ||||
| Mean blood pressure >93 mmHg | SVR+ | 0.342 (0.069, 1.703) | 0.36 | ||
| SVR++ | 1.825 (0.698, 4.766) | ||||
| LV ejection fraction (per 5% increment) | SVR+ | 0.969 (0.642, 1.462) | 0.90 | ||
| SVR++ | 1.091 (0.796, 1.494) | ||||
| LV end-diastolic volume < 90 mL.m-2 | SVR+ | 1.048 (0.276, 3.978) | 0.048 | 1.227 (0.290, 5.208) | 0.022 |
| SVR++ | 6.679 (2.075, 21.491) | 6.666 (1.733, 25.641) | |||
| LV end-systolic volume < 50 mL.m-2 | SVR+ | 0.833 (0.220, 3.156) | 0.36 | ||
| SVR++ | 2.500 (0.922, 6.782) | ||||
| LV mass (per 10 g.m-2) | SVR+ | 1.055 (0.532, 2.092) | 0.70 | ||
| SVR++ | 0.731 (0.431, 1.238) | ||||
| LV concentric remodeling index>0.58 | SVR+ | 0.335 (0.066, 1.700) | 0.17 | ||
| SVR++ | 2.927 (1.040, 8.235) | ||||
| MI volume at MRI (% of LV) | SVR+ | 1.189 (0.678, 2.084) | 0.90 | ||
| SVR++ | 0.951 (0.632, 1.432) | ||||
| Microvascular obstruction | SVR+ | 1.374 (0.722, 2.616) | 0.82 | ||
| (per 10% of LV increment) | SVR++ | 1.044 (0.600, 1.819) | |||
| Stroke volume index >38 mL.m-2 | SVR+ | 0.765 (0.207, 2.828) | 0.048 | ||
| SVR++ | 0.127 (0.035, 0.464) | ||||
| Cardiac index >2.4 L.min-1.m-2 | SVR+ | 0.731 (0.198, 2.704) | 0.06 | ||
| SVR++ | 0.172 (0.054, 0.552) | ||||
| SVR (mmHg.min.m2.L-1) | SVR+ | 0.914 (0.824, 1.013) | 0.03 | 0.905 (0.812, 1.008) | 0.003 |
| SVR++ | 1.123 (1.044, 1.208) | 1.109 (1.031, 1.194) | |||
eGFR: estimated glomerular filtration rate; LV, left ventricle; MI: myocardial infarction; NGAL, Neutrophil Gelatinase-Associated Lipocalin; SVR, systemic vascular resistances.