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. 2020 Mar 26;5(6):e129034. doi: 10.1172/jci.insight.129034

Figure 2. Empagliflozin suppressed the mesenchymal phenotypes in the proximal tubules in diabetic mice.

Figure 2

(A–H) EMT analysis. E-cadherin–positive/αSMA-positive cells (A–D) and E-cadherin–positive/vimentin-positive cells (E–H) were recognized as cells undergoing the EMT. For each group of mice. n = 5. Scale bar: 50 μm. (I–P) Immunofluorescence for aminopeptidase A/αSMA and uromodulin/αSMA in kidney sections. Deparaffinized sections were analyzed from each group of mice. n = 5. Scale bar: 50 μm. Empa, empagliflozin.