KEY RESOURCES TABLE

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
HA Epitope Tag Antibody, Alexa Fluor 488 conjugate (16B12)	Thermo Fisher Scientific	Cat#A-21287 RRID: AB_2535829
Bacterial and Virus Strains
Biological Samples
Chemicals, Peptides, and Recombinant Proteins
EDTA-free complete protease inhibitor cocktail tablets	Roche	Cat#5056489001
Iodoacetamide	Sigma	Cat#I1149
n-dodecyl-beta-D-maltopyranoside (DDM)	Anatrace	Cat#D310
Cholesterol hemisucinate (CHS)	Sigma	Cat#C6512
TALON IMAC resin	Clontech	Cat#635507
1-palmitoyl-2-oleoyl-glycero-3-phosphocholine (POPC)	Avanti	Cat#850457
1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (POPS)	Avanti	Cat#840034
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(cap biotinyl)	Avanti	Cat#870273
Bio-Beads™ SM-2 Resin	Bio-rad	Cat#1523920
[3H]-CGP-12177	Perkin Elmer	Cat# NET106250UC
MultiLex A	Perkin Elmer	Cat# 1450-441
Filtermat A	Perkin Elmer	Cat# 1450-421
Glucose oxidase	Sigma-Aldrich	Cat# G2133
Catalase	Sigma-Aldrich	Cat# C3155
Neutravidin	Thermo Fisher	Cat# 31000
Cy3 maleimide	GE Healthcare	Cat# PA13131
ß2AR	This work	N/A
ß2AR[AA]	This work	N/A
Membrane scaffold protein 1 (MSP1)	This work	Ritchie et al., 2009
Critical Commercial Assays
Deposited Data
Experimental Models: Cell Lines
Spodoptera frugiperda (Sf9) insect cells	Gibco
Bac-to-Bac™ Baculovirus Expression System	Thermofisher	Cat# 10359016
Experimental Models: Organisms/Strains
Oligonucleotides
Recombinant DNA
Human ß2AR genes	genescript	N/A
Software and Algorithms
Prism GraphPad	https://www.graphpad.com	N/A
IDL	https://www.harrisgeospatial.com	version 8.1
HaMMy	McKinney et al., 2006	N/A
Single	https://physics.illinois.edu/cplc/software/)	N/A
Igor Pro	https://www.wavemetrics.com	Igor Pro 6.3
Molsoft	Molsoft, LLC
Other